FIV după 40 de ani: șanse de succes, protocoale și opțiuni
Fertilizarea in vitro după 40 de ani: rate reale de succes, protocoale speciale, ovocite donate vs proprii, PGT-A și strategii de optimizare.

Întrebări frecvente
Navot D, Bergh PA, Williams MA, Garrisi GJ, Guzman I, Sandler B, Grunfeld L Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility. The Lancet, 1991.
DOI: 10.1016/0140-6736(91)91382-3Munne S, Kaplan B, Frattarelli JL, Child T, Nakhuda G, Shamma FN, Silverberg K, Kalista T, Handyside AH, Katz-Jaffe M, Wells D, Gordon T, Stock-Myer S, Willman S Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial. Fertility and Sterility, 2019.
DOI: 10.1016/j.fertnstert.2019.07.1346Budak E, Garrido N, Soares SR, Melo MA, Meseguer M, Pellicer A, Remohi J Improvements achieved in an oocyte donation program over a 10-year period: sequential increase in implantation and pregnancy rates and decrease in high-order multiple pregnancies. Fertility and Sterility, 2007.
DOI: 10.1016/j.fertnstert.2006.06.050Sunkara SK, Rittenberg V, Raine-Fenning N, Bhattacharya S, Zamora J, Coomarasamy A Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles. Human Reproduction, 2011.
DOI: 10.1093/humrep/der106ESHRE Working Group on ART Registries ART in Europe, 2019: results generated from European registries by ESHRE. Human Reproduction, 2023.
DOI: 10.1093/humrep/dead197Ubaldi FM, Cimadomo D, Vaiarelli A, Fabozzi G, Venturella R, Maggiulli R, Mazzilli R, Ferrero S, Palagiano A, Rienzi L Advanced maternal age in IVF: still a challenge? The present and the future of its treatment. Frontiers in Endocrinology, 2019.
DOI: 10.3389/fendo.2019.00094Franasiak JM, Forman EJ, Hong KH, Werner MD, Upham KM, Treff NR, Scott RT Jr The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening. Fertility and Sterility, 2014.
DOI: 10.1016/j.fertnstert.2013.11.004Gleicher N, Kushnir VA, Barad DH Prospectively assessing risk for premature ovarian senescence in young females: a new paradigm. Reproductive Biology and Endocrinology, 2015.
DOI: 10.1186/s12958-015-0034-zPractice Committee of the American Society for Reproductive Medicine Testing and interpreting measures of ovarian reserve: a committee opinion. Fertility and Sterility, 2020.
DOI: 10.1016/j.fertnstert.2020.09.134Cimadomo D, Fabozzi G, Vaiarelli A, Ubaldi N, Ubaldi FM, Rienzi L Impact of maternal age on oocyte and embryo competence. Frontiers in Endocrinology, 2018.
DOI: 10.3389/fendo.2018.00327


