Testarea genetică preimplantare (PGT): PGT-A, PGT-M, PGT-SR — ghid complet
Dr. Mihaela BragaTestarea genetică preimplantare: tipuri (PGT-A aneuploidii, PGT-M monogenice, PGT-SR structurale), indicații, procedura biopiei trofoblastice și beneficii.
Întrebări frecvente
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DOI: 10.1016/j.fertnstert.2013.11.004Scott RT Jr, Upham KM, Forman EJ, Hong KH, Scott KL, Taylor D, Tao X, Treff NR Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertility and Sterility, 2013.
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DOI: 10.1016/j.fertnstert.2017.07.1168Greco E, Minasi MG, Fiorentino F Healthy babies after intrauterine transfer of mosaic aneuploid blastocysts. New England Journal of Medicine, 2015.
DOI: 10.1056/NEJMc1500421Munné S, Kaplan B, Frattarelli JL, Child T, Nakhuda G, Shamma FN, Silverberg K, Kalista T, Handyside AH, Katz-Jaffe M, Wells D, Gordon T, Stock-Myer S, Willman S Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial. Fertility and Sterility, 2019.
DOI: 10.1016/j.fertnstert.2019.07.1346Scriven PN, Ogilvie CM Fluorescence in situ hybridization on single cells. Methods in Molecular Medicine, 2007.
DOI: 10.1385/1-59745-497-7:31Zegers-Hochschild F, Adamson GD, Dyer S, Racowsky C, de Mouzon J, Sokol R, Rienzi L, Sunde A, Schmidt L, Cooke ID, Simpson JL, van der Poel S The International Glossary on Infertility and Fertility Care, 2017. Human Reproduction, 2017.
DOI: 10.1093/humrep/dex234Forman EJ, Hong KH, Ferry KM, Tao X, Taylor D, Levy B, Treff NR, Scott RT Jr In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial. Fertility and Sterility, 2013.
DOI: 10.1016/j.fertnstert.2013.02.056PGDIS Position Statement on the Transfer of Mosaic Embryos PGDIS position statement on chromosome mosaicism and preimplantation aneuploidy testing at the blastocyst stage. Reproductive BioMedicine Online, 2021.
DOI: 10.1016/j.rbmo.2021.02.010Viotti M, Victor AR, Barnes FL, Zouves CG, Besser AG, Grifo JA, Cheng EH, Lee MS, Horcajadas JA, Corti L, Fiorentino F, Spinella F, Minasi MG, Greco E, Munné S Using outcome data from one thousand mosaic embryo transfers to formulate an embryo ranking system for clinical use. Fertility and Sterility, 2021.
DOI: 10.1016/j.fertnstert.2020.11.041
